"A living Nuclear Weapon destined to walk the Earth forever. Indestructible" - Dr. Hayashida Godzilla 1984
Zacama lends naturally to combos, with the untap shenanigans and numerous tech he's even the heart of several combos.
Kiki-Jiki, Mirror Breaker + Zealous Conscripts
one of the standard red combos, costs a lot to hard cast but it does swarm the field with infinite Conscripts tokens, luckily we're playing Naya so we can also use,
Tooth and Nail
allowing us for 9 mana to entwine and drop both of these on the field! Can add
Impact Tremors
for infinite damage.
Kiki-Jiki, Mirror Breaker + Village Bell-Ringer
same as Conscripts above but costs less to hard cast! Can also be
Tooth and Nail
entwined to get both to the field from deck.
Karmic Guide + Kiki-Jiki, Mirror Breaker + Zealous Conscripts
this combo requires both Kiki and Conscripts in grave we cast Guide, get Kiki, who taps to make a Guide token, who grabs Conscripts who untaps Kiki which then begins to make infinite Conscripts. Can add
Impact Tremors
for infinite damage.
Karmic Guide + Kiki-Jiki, Mirror Breaker + Village Bell-Ringer
same as the combo above but with Bell-Ringer.
Impact Tremors + Karmic Guide
+ Kiki-Jiki, Mirror Breaker + Zealous Conscripts
Infinite damage and Infinite Conscripts.
Impact Tremors + Karmic Guide
+ Kiki-Jiki, Mirror Breaker + Village Bell-Ringer
Same as above but with Bell-Ringer
Karmic Guide + Mirror Entity + Reveillark
+
Impact Tremors
this is infinite LTBs and ETBs triggering infinite damage from Impact Tremors this is due to Mirror Entity's effect essentially working like a mass sac outlet.
Ashnod's Altar + Melira, Sylvok Outcast + Woodfall Primus
or
Goblin Bombardment
this is infinite ETBs with Woodfall destroying everything your opponents control that isn't a creature, can add
Impact Tremors
for infinite damage. Can also add
Fecundity
for infinite draw!
Food Chain
+
Eternal Scourge
or
Squee, the Immortal
+
Impact Tremors
Food chain the bread and butter of this deck, it allows us to get infinite mana to cast any creature and allows us to infinitely cast either Scourge or Squee, adding Impact Tremors into this allows us to deal infinite damage as well.
Food Chain
+
Eternal Scourge
or
Squee, the Immortal
+
Zacama, Primal Calamity
why not have infinite mana for not just creatures but for every spell? This combo lets us etb Zacama as many times as we want blow up every artifact and enchantment, burn down every creature and gain infinite life. A couple other cards can add to this as well, things like
Genesis Wave
for getting our whole deck on the field, or
Beast Whisperer
for infinite draw.
Food Chain
+
Eternal Scourge
or
Squee, the Immortal
+
Walking Ballista
This allows us to drop an infinite power Ballista which annihilates all our opponents.
Food Chain
+
Eternal Scourge
or
Squee, the Immortal
+
Aetherflux Reservoir
This creates infinite life which allows us to use Aetherflux to slam 50 damage into every opponent.
Food Chain
+
Eternal Scourge
or
Squee, the Immortal
+
Zacama, Primal Calamity
+
Mycosynth Lattice
This makes Zacama's destroy target artifact or enchantment into destroy target everything an opponent has an be the only one standing.
Birds of Paradise
+
Zendikar Resurgent
+
Cloudstone Curio
+
Zacama, Primal Calamity
This is a strange combo and I bet you're thinking when has Birds EVER been a combo piece? Well you're seeing it now! Simply put lets say Resurgent is on the battlefield but we only got 9 mana, we have 9 lands though I know we'd realistically have 18 mana but this is just for this example.
Birds is untapped, you tap Birds for one then cast Zacama, now we have all 9 lands untapped and we draw a card, and bounce Birds from Curio. We use the floating to cast Birds draw a card, and bounce Zacama to the hand and recast Zacama we now have 9 floating mana and untapped our lands again. As you can see this combo lets us draw our entire deck well gaining us infinite mana!
Temur Sabertooth
+
Zendikar Resurgent
+
Zacama, Primal Calamity
similar to the above combo but require less pieces I think this is probably the most optimal version of the combo since it has less pieces although Sabertooth draws hate quickly and can get removed hard. Not that Curio doesn't draw hate but in my experience people tend to disrupt a creature quicker then the Curio. Same outcome as the Combo above since you cast Zacama, have 18 mana bounce him recast and then draw the deck.
Personally I think the Birds combo is flashier and much more humorous since, you know Birds as a combo piece but this once is reliable and gets the job done.
There are a few combos here where if you add
Temur Sabertooth
or
Cloudstone Curio
the same effect happens I did not list those but they are there!