So there has been 2 consistent issues with the deck as I've been playing it.
The first, is that a lot of aggro decks, Affinity especially, are a nightmare match up. Honestly I don't even get to play Magic with this deck, I just slump over and die. So I looked to Modern Dredge to see how they dealt with the Robo-Menace since they are the closest top tier strategy to what this deck is trying to do. I discovered that in most cases Dredge has no problem with Affinity thanks to a wonderful card called Conflagrate. So I just had to find space for it somewhere in the list, but what to take out?
This leads me to problem #2. In this deck Prized Amalgam sucks. It's a shock I know! But honestly Amalgam coming into play tapped is a huge issue for this deck in two ways. The first, is that because it comes into play tapped it can't act as an aggressive creature. As such it doesn't pair up well with Bloodghast or Vengevine to kill our opponent out of nowhere. It comes into play, gives our opponent a turn to set up blockers, and then can attack. Not at all ideal. The 2nd issue again comes from it coming into play untapped, you can't block with it! There are scenarios where you set up Vengevine to block a lethal attack, and on the next turn reanimate it and swing for lethal. But you can't do this with Amalgam. It coming into play tapped makes both ends of combat extremely awkward, so it's getting axed from the list.
So we want to put in Conflagrate, but do we have enough cards in our hand often enough to make it good? Driven / Despair says we do! Not only does this card draw us a hell ton of cards, it also throws trample on our creatures. When you're swinging at your opponent with something 4 or more 4 power creatures, throwing Trample on them is sometimes more than enough to just win you the game on the spot. And if they survive we just drew enough cards to Conflagrate them to death. And then there is the Despair backend to the card, which adds more evasion to our creatures, while also giving the card use if we discard it to one of our many discard outlets. This card is sweet.
I'm also going down a copy of Collective Brutality in the mainboard because while the card is really good, it isn't a card I want to see every game.
Finally because we're increasing our spell count, we're taking out a Lotleth Troll and putting in 2 Noose Constrictor. This makes us able to discard cards consistently even if we draw a bunch of non-creature cards.