So I think really this may be a thing more for a spell based deck, but what about finding space for an Dramatic reversal + Isochron Scepter infinite mana combo?

It's more of a "cute" combo. Although it can be a good way of making large amounts of mana it would not synergies well with the rest of my deck. I'm not running much in the way of instances to make Isochron Scepter useful.

Yeah, probably should have figured. Although, while I have your ear, could you recommend a commander to sue such a combo? I do know another creature I'd use would be Elite Arcanist, as he can do the same thing as the scepter, but really I don't know mono blue enough to know what commander to abuse it with.

i know it is being tested to great success in cEDH UB Oona, Queen of the Fae storm, which could be mono U though it gets much worse

Elite Arcanist, Isochron Scepter, and Dramatic reversal seem like they would work wonders in a wizard tribal Azami, Lady of Scrolls deck. The untapping of all nonland permanents would synergise well with Azami, Lady of Scrolls card drawing ability.